Previous studies have shown that wild-type (wt) rabies virus (RABV) evades the host immune response by restricting expression of glycoprotein (G), which blocks activation of dendritic cells (DCs) and induces production of virus-neutralizing antibodies (VNAs).In the present study, wt RABVs not only restricted G expression but also reduced incorporat
Prehistoric archaeological research in Indonesia recently showed the existence of dwelling caves from the late Pleistocene, starting from Sumatra, Java, Sulawesi to East Nusa Tenggara.The Song Gede site is one of the dwelling caves from the late Pleistocene which was very interesting to be discused, especially when tracing the distribution of early
Signaling networks that convert graded stimuli into binary, all-or-none cellular responses are critical in processes ranging from cell-cycle control to lineage commitment.To exhaustively enumerate topologies that exhibit this switch-like behavior, we simulated all possible two- and three-component networks on random parameter sets, and assessed the
Interventions for job interviews targeting the impaired theory of mind observed in Default individuals with autism spectrum disorders (ASD) are limited.We developed a role-play-based guidance system for job interviews using an android robot resembling a real person.Individuals with ASD worked in pairs and played dual roles in mock job interviews.Sp
Motility is finely regulated and is crucial to bacterial processes including colonization and biofilm formation.There is a trade-off between motility and growth in bacteria with molecular mechanisms not fully understood.Hypermotile Escherichia coli could be isolated by evolving non-motile cells on soft agar plates.Most of the isolates carried mutat